Dr. Donna H. Ryan (Click to learn more about Dr. Donna H. Ryan)
The 𝐂𝐫𝐨𝐚𝐢𝐞® 𝐒𝐌𝐆𝐓-𝐆𝐋𝐏-𝟏 𝐍𝐚𝐧𝐨 𝐌𝐢𝐜𝐫𝐨𝐧𝐞𝐞𝐝𝐥𝐞 𝐏𝐚𝐭𝐜𝐡 has been meticulously developed by The Obesity Society. Designed by a team of leading experts in obesity management, this cutting-edge product was created following years of in-depth research and a comprehensive understanding of the mechanisms involved in weight loss and obesity control. Its unique formulation is designed to effectively promote weight loss, maintain stable blood sugar levels, and enhance metabolic balance, while incorporating Matrixyl 3000 to deliver significant lifting and firming effects, helping users improve body shape and skin condition more comprehensively, thus supporting them in achieving their health goals.
This nano microneedle patch utilizes advanced SMGT-GLP-1 technology, delivering active ingredients precisely to the deeper layers of the skin. It scientifically regulates insulin secretion, suppresses glucagon, delays gastric emptying, and assists in controlling blood sugar levels, thereby promoting healthy fat reduction and optimizing overall health management. Meanwhile, Matrixyl 3000 stimulates skin regeneration, enhancing skin firmness, allowing users to maintain tight and smooth skin while losing weight.
Let’s take a look at what makes the Croaie® SMGT-GLP-1 Nano Microneedle Patch so special.

The Nano Microneedle Patch contains SMGT-GLP-1 in each patch. It works by mimicking the action of Glucagon-like Peptide-1 (GLP-1), promoting insulin secretion, inhibiting glucagon secretion, and delaying gastric emptying, which helps control blood sugar levels and aids in weight loss.
To enhance the overall slimming and firming effect, the patch is also infused with Matrixyl 3000 — a powerful peptide complex known for its ability to stimulate collagen production, visibly tighten skin, and reduce the appearance of fine lines and sagging often associated with rapid weight loss.
Typically, SMGT-GLP-1 is administered via injection, providing fast results in a short period. However, the effects do not last long, and it may lead to stress reactions, requiring multiple injections in a short time, which is time-consuming and expensive.
The Croaie® SMGT-GLP-1 Nano Microneedle Patch offers a long-lasting, slow release of the medication, ensuring a stable effect over 24 hours without causing any discomfort. With the same dosage and price, it can maintain up to 20 times longer-lasting effects (similar to the difference between an IV drip and a single injection).




Let’s take a look at some of the cases from our users
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“I suffer from both obesity and diabetes, and I had been receiving SMGT-GLP-1 (also known as semaglutide) treatments at the hospital. You might wonder why I suddenly switched to the Croaie Nano Microneedle Patch. Honestly, semaglutide is an excellent treatment — shortly after each injection, my appetite decreased, I lost weight quickly, and my blood sugar levels dropped.But sticking to regular injections isn’t easy. On injection days, I’d always find excuses to skip — the cost, the hunger, scheduling conflicts, or even something as simple as bad weather would stop me. Over time, this inconsistency affected the results.That’s why the Croaie® Nano Microneedle Patch is perfect for someone like me who struggles with consistency. I can apply it easily at home, and the slow-release formula works for a full 24 hours, helping me control my appetite steadily. Plus, it’s very affordable — it makes SMGT-GLP-1 accessible for anyone looking to lose weight and manage their blood sugar.What surprised me even more is that Croaie is different from other fast weight-loss products. My skin didn’t sag after losing weight — instead, it became noticeably firmer and more toned during the process.“
“For all these years, I’ve really been “fighting” with my diet. As a diabetic, there are so many things I can’t eat—just a little slip-up and my blood sugar spikes. What’s even more frustrating is that despite all my efforts, my weight hasn’t changed at all, and my blood sugar is still all over the place. My doctor even told me that some foods might help with weight loss, but they don’t do anything for blood sugar control, which was so disheartening.I’ve also tried other weight loss products before—yes, I lost a bit of weight, but my skin ended up loose and saggy, and I looked more tired and drained. But the Croaie® Nano Microneedle Patch is different. It contains Matrixyl 3000, and the firming effect is really noticeable—my skin not only didn’t loosen, it actually feels firmer! I’ve used it consistently for 84 days, and the results are amazing: I’ve lost several kilos, my blood sugar is back to normal, and I look younger. My friends have even commented on how much more vibrant I look! It’s so easy to use—just once a week—and I can eat whatever I want, and it helps automatically control my portion sizes. It’s honestly incredible!
If I hadn’t seen the promotion for this product by chance at the pharmacy, I might have never discovered such an amazing gem.”
I’m 37 years old, and after having my second child, my belly turned into the typical “mommy belly” – loose and wrinkled. I felt terrible and didn’t even want to exercise because my belly would jiggle with every step. I tried cocoa butter and massages for two months, but nothing really changed. My doctor suggested surgery, but I didn’t want any scars or the high costs. So, my husband ordered the CROAIE Nano Microneedle Patch with SMGT-GLP-1 and Matrixyl 3000 for me. Not only does it help with weight loss, but it also tightens my skin, and it feels amazing. I use it every day, and by the fifth day, I could feel my skin tightening, and I noticed a significant weight drop. After two weeks, my belly was completely back to normal – no wrinkles, no sagging, just firm like when I was 20. I’m planning to get some for my 60-year-old mom next because I believe it will work wonders for her aging arms too.
Liora Pendleton,Brookfield, WI 53045, USA
It wasn’t until I started having foot problems that I realized how much high blood sugar levels were affecting my daily life. It was then that I decided to try this 𝐶𝑟𝑜𝑎𝑖𝑒® Drops. Not only have my blood sugar levels stabilized, but the good circulation supports the proper healing of my feet, which I might otherwise have amputated.
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